This is a great website for planning your route and your stops.  It has an excellent interactive map that allows the user to turn on and off layers including, hotels, restaurants, campgrounds, points of interest, natural wonders, parks, gardens, and more.  It tallies your total mileage, travel time and includes an estimate for fuel expenses that updates as you alter your route.  Depending on what your interests are, just turn on the layers and you'll be sure not to miss anything along the way.